Frequently Asked

Psilocybin microdosing is the practice of consuming very small, sub-perceptual doses of psilocybin on a regular basis. Microdosing typically involves taking a fraction of a standard recreational dose, often 1/10th or 1/20th of a full dose. The aim of microdosing is to experience subtle, noticeable effects without the intensity of a full psychedelic experience.
There are a range of benefits, including increased creativity, focus, energy, and improved mood. Some have also reported improved executive functions, reduced anxiety and depression symptoms, and heightened spiritual or introspective experiences.
Given the lack of standardized guidelines, recommended dosages for psilocybin microdosing can vary. However, a common approach is to take approximately 1/10 to 1/20 of a standard psychedelic dose. This typically translates to a dosage range of 0.1 to 0.3 grams. Sila has 0.2 grams in each sachet.
The frequency of psilocybin microdosing can vary depending on individual preferences and goals. There is no universally agreed-upon standard, as it can be influenced by desired effects, personal response, and tolerance. However, a common microdosing regimen is to take a dose every three to four days, with two consecutive days of rest in between. This allows for potential tolerance to subside and helps maintain the effectiveness of the microdose. We at Sila recommend one-day-on-one-day-off.
Currently, there are no proven risks or side effects. Yu et al. (2022) has reported that the consumption of microdose psilocybin has been associated with an increase in systolic and diastolic blood pressure. They concluded that the cardiovascular safety was not of a concern since the increase caused by psilocybin itself is minimal. Vollenweider et al, 1998 has reported that a significant dose of psilocybin can induce schizophrenia-like symptoms in individuals with environmental and genetic vulnerabilities. However, this is extremely rare and not a concern with microdose.
Generally, the effects of a microdose are subtle and may not be immediately noticeable. However, some report an uplifted mood, and increased positivity within the first hour or two after ingestion. The effects of a microdose are often described as a mild shift in consciousness or a subtle enhancement of mental state rather than a full-blown psychedelic experience. Many people who microdose report experiencing effects throughout the day, typically lasting between 4 to 8 hours. However, it’s important to note that the duration and intensity of effects can be influenced by various factors, including individual metabolism, dose size, and sensitivity to psilocybin.
Psilocybin microdosing is an area of interest for potential therapeutic applications, however, it’s important to note that research on the specific benefits and effects of microdosing is still in early stages. Most of the existing research on psilocybin has focused on larger, therapeutic doses rather than microdoses.

Here are some general guidelines to consider:

  • Start with a low dose: Begin with a conservative dose, we recommend starting with half a sachet (0.1 grams). 
  • Use reliable and tested sources: Ensure you obtain your psilocybin mushrooms from a reputable source that follows proper cultivation and safety standards. It’s crucial to have confidence in the quality and purity of the product you are consuming.
  • Set and setting: Create a comfortable and supportive environment for your microdosing sessions. Choose a calm and familiar space where you feel safe and relaxed. Consider factors like lighting, music, and the presence of trusted individuals who can provide support if needed.
  • Maintain a microdosing schedule: Establish a consistent schedule for microdosing sessions. This can help maintain a sense of routine and allow for better self-assessment of the effects. We recommend following a one-day-on-one-day-off schedule. 
  • Keep a journal: Maintain a journal to track your experiences and observations. Record details such as the dose, time, effects, mood, and any insights or changes you notice. This can help you gain insights into your microdosing journey and evaluate its effectiveness.
  • Be mindful of interactions: If you are taking any medications or supplements, it’s important to research and understand their potential interactions with psilocybin. Certain medications, particularly those that affect serotonin levels, can interact with psilocybin and lead to adverse effects. Consult with a healthcare professional.
  • Integration and support: Microdosing can bring about profound experiences and insights. It can be valuable to engage in integration practices such as journaling, meditation, therapy, or discussions with trusted individuals to help process and integrate the effects into your daily life.
It’s crucial to approach the combination of psilocybin microdosing with other medications or substances with caution. Here are some important considerations:
  • Medication interactions: Psilocybin can interact with medications, including but not limited to antidepressants, antipsychotics, and MAO inhibitors. These interactions can lead to unwanted side effects or diminish the effectiveness of the medications. Please consult with a healthcare professional to evaluate any potential interactions and determine if microdosing is safe in combination with your current medications.
  • Substances with similar effects: Combining psilocybin microdosing with other substances such as alcohol, cannabis, or other psychedelics that have psychoactive effects, can amplify the effects and increase the risk of adverse reactions. Mixing substances may also interfere with your ability to accurately assess the effects of microdosing or lead to an unpredictable response.
  • Personal tolerance and sensitivity: Individual tolerance and sensitivity to substances can vary. What may be well-tolerated by one person could have different effects or risks for another. It’s important to understand your own body’s response and take that into consideration when contemplating any substance combinations.
  • Health conditions: Certain health conditions may make it inadvisable to combine psilocybin microdosing with other substances. For example, individuals with cardiovascular issues or a history of substance abuse may have increased risks associated with combining substances. 
In all cases, it is highly recommended to consult with a healthcare professional who is knowledgeable about psychedelics and understands your medical history before considering combining psilocybin microdosing with other medications or substances. They can provide personalized guidance based on your individual circumstances, help evaluate potential risks and benefits, and ensure your safety and well-being.
Store in a cool dry place.
Sila is pre-measured to offer you consistent dosing, and consistent results!
Assessing the effects of psilocybin microdosing can be a subjective process, as the experiences and benefits can vary between individuals. Here are some indicators that can help you determine if psilocybin microdosing is working for you: Self-reflection and introspection Pay attention to your thoughts, emotions, and overall state of mind. Reflect on whether you notice any changes in your mental and emotional well-being. Some individuals report increased introspection, enhanced mood, or improved emotional resilience as positive effects of microdosing. Increased focus and productivity  Observe whether you experience improvements in your ability to concentrate, be productive, or engage in creative or problem-solving tasks. Enhanced cognitive function and productivity are commonly reported benefits of microdosing. Creativity and cognitive flexibility  Notice if you experience an expansion of creativity, novel ideas, or enhanced cognitive flexibility. Some individuals find that microdosing helps them think outside the box, approach problems from new perspectives, and unleash their creative potential. Mood enhancement  Check for changes in your overall mood and emotional well-being. Microdosing has been reported to potentially alleviate symptoms of anxiety and depression, leading to an overall improvement in mood and a greater sense of well-being. Increased energy and motivation  Pay attention to any changes in your energy levels or motivation. Some individuals report feeling more energized, motivated, and engaged in their daily activities after microdosing. Personal goals and intentions Assess whether microdosing aligns with your personal goals and intentions. If you are seeking specific improvements in your life, such as increased productivity, emotional well-being, or creativity, evaluate if microdosing is helping you move closer to those goals. It’s important to remember that the effects of microdosing can be subtle and may not be immediately noticeable. Keeping a journal or record of your experiences can be helpful in tracking any changes or patterns over time. Additionally, the effects of microdosing can vary between individuals, and what works for one person may not work the same way for another. It’s crucial to give yourself time to experiment with different dosages, schedules, and observe how it affects you personally. If you have any concerns or are unsure about the effects of microdosing, it’s recommended to consult with a healthcare professional who is knowledgeable about psychedelics. They can provide guidance, help interpret your experiences, and assist in assessing the effectiveness of microdosing for your specific needs.
Yes, one of the goals of psilocybin microdosing is to allow you to engage in daily activities while experiencing subtle effects. Microdoses are sub-perceptual, meaning the effects are not intended to be strong enough to interfere with your ability to function in everyday life. Here are a few points to keep in mind:
  • Start with a low dose: Begin with a conservative microdose to gauge how it affects you individually. We recommend starting with half a SILA sachet. 
  • Maintain a consistent schedule: Establish a regular microdosing schedule that works for you. Consistency can help you better understand the effects and integrate microdosing into your daily routine. We recommend a one-day-on-one-day-off schedule.
  • Evaluate your response: Pay attention to how you feel and function during microdosing days. Assess if there are any noticeable changes in your mood, energy, focus, or cognition. If you feel any discomfort, impairment, or find it challenging to perform tasks, it may be necessary to adjust the dosage or timing.
Remember, responsible use and self-assessment are key. If you have any concerns or questions about microdosing and its potential effects on your daily activities, it’s recommended to consult with a healthcare professional who is knowledgeable about psychedelics. They can provide guidance tailored to your specific circumstances.
Psilocybin microdosing and macrodosing refer to two different approaches to consuming psilocybin. Here’s a breakdown:
  • Dosage: Microdosing involves taking very small, sub-perceptual doses of psilocybin. Typically, microdoses are 1/10th to 1/20th of a standard recreational dose. The goal is to experience subtle effects that are often described as a mild shift in consciousness without the intensity of a full psychedelic experience.
On the other hand, macrodosing refers to taking a full or higher dose of psilocybin, which induces a full psychedelic experience. This dosage is sufficient to produce profound alterations in perception, including visual hallucinations, intense emotions, and deep introspection.
  • Intended effects: Microdosing is often pursued for its potential cognitive, mood-enhancing, and creative benefits. People who microdose may report increased focus, productivity, creativity, and improved overall well-being. The effects are typically described as subtle and functional, allowing individuals to engage in their regular daily activities without significant impairment.
Macrodosing, however, is sought after for its more pronounced and transformative effects. A macrodose experience can lead to profound introspection, emotional release, spiritual insights, and a sense of interconnectedness. It is often seen as a tool for personal growth, self-exploration, and therapeutic purposes.
  • Frequency and duration: Microdosing regimens usually involve taking a microdose every few days or on specific days of the week, followed by days of rest to prevent tolerance buildup. This schedule aims to maintain a consistent, sub-perceptual level of psilocybin in the system.
Macrodosing is typically done less frequently, with longer intervals between experiences. It’s common for individuals who engage in macrodosing to space out their sessions by weeks or even months to integrate and process the profound experiences.
  • Setting and intention: Microdosing is often incorporated into one’s daily routine, allowing individuals to engage in regular activities such as work, study, and social interactions. The focus is on functional enhancement and subtle effects.
Macrodosing, on the other hand, is often done in a carefully prepared and controlled environment, with attention given to set and setting. A macrodose experience is typically approached with a specific intention, and individuals may create a conducive setting that supports the transformative and potentially intense nature of the experience.
Microdosing can be practiced with various psychedelics, not just psilocybin. While psilocybin is one of the more commonly used substances for microdosing, other psychedelics can also be microdosed. Each substance has its own unique effects and considerations, so it’s important to research and understand the specific characteristics of the psychedelic you choose to microdose with.
Tolerance to psilocybin and other psychedelics can develop with repeated use, including microdosing. When you consume a substance like psilocybin, your body and brain adapt to its effects, resulting in a diminished response over time. To mitigate tolerance buildup and maintain the effectiveness of microdosing, you can consider the following strategies:
  1. Schedule breaks: Taking regular breaks from microdosing can help prevent or reduce tolerance buildup. We recommend a microdosing regimen of one day on and one day off. This intermittent schedule allows your body to reset and regain sensitivity to the substance.
  2. Adjust dosage: Instead of increasing the dosage when tolerance develops, it may be more effective to lower the dose. By decreasing the amount of psilocybin consumed during microdosing, you may be able to maintain the sub-perceptual effects while mitigating tolerance.
  3. Cyclical or intermittent use: Instead of continuous microdosing, you can consider using psilocybin in cycles. For example, you might microdose for several weeks and then take an extended break to allow your body to reset before starting a new cycle. This approach can help minimize tolerance and allow for a more sustainable long-term microdosing practice.
  4. Individual experimentation: Since everyone’s body and response to substances are unique, it may be necessary to experiment and find the approach that works best for you. Some individuals may find that shorter or longer breaks between microdoses, different dosages, or alternative schedules yield better results in mitigating tolerance.
It’s important to note that scientific research on the long-term effects and strategies to mitigate tolerance with psilocybin microdosing is limited. Therefore, it’s advisable to consult with a healthcare professional who is knowledgeable about psychedelics for personalized guidance and support in managing tolerance and optimizing your microdosing regimen.

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There is no universally agreed-upon ideal time of day for psilocybin microdosing. The timing of your microdose can vary based on personal preference and your desired outcomes. Some individuals prefer to take their microdose in the morning to experience the effects throughout the day, while others may choose to take it in the afternoon or evening. Here are a few factors to consider when deciding on the timing of your psilocybin microdose:
  1. Personal Schedule: Consider your daily routine and activities. It may be helpful to choose a time when you can fully engage in your regular tasks and responsibilities without interruption or interference.
  2. Individual Response: Pay attention to how psilocybin affects you personally. Some individuals may find that microdosing in the morning provides a subtle energy and focus boost for the day ahead. Others may prefer taking it in the afternoon or evening to facilitate relaxation, introspection, or creative pursuits.
  3. Sleep Quality: Psilocybin can affect sleep patterns for some individuals, potentially causing difficulties falling asleep. If you experience any sleep disturbances, it may be advisable to avoid taking your microdose too late in the day to minimize any potential impact on your sleep.
  4. Duration of Effects: The duration of psilocybin microdose effects varies from person to person. Generally, the effects of a microdose can last between 4 to 8 hours, with some residual effects potentially lasting longer. Consider how the timing aligns with your desired outcomes and the duration of effects that work best for your daily activities.
Ultimately, finding the ideal time for your microdose may involve some experimentation and self-observation. Start with a conservative dose and try different timing options to assess how it affects your energy, focus, mood, and overall well-being throughout the day. It’s important to note that individual responses to microdosing can vary, and what works best for one person may not be the same for another. If you have specific concerns or questions about the timing of your microdose, it’s recommended to consult with a healthcare professional who is knowledgeable about psychedelics for personalized guidance and support.

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